3-Bromo-5-methoxy-4-(4-methylpiperidin-1-yl)furan-2(5H)-one
نویسندگان
چکیده
There are two molecules in the asymmetric unit of title compound, C(11)H(16)BrNO(3), which was obtained via the tandem Michael addition-elimination reaction of 3,4-dibromo-5-meth-oxy-furan-2(5H)-one and 4-methyl-piperidine in the presence of potassium fluoride. The furan-one rings are approximately planar [maximum atomic deviations of 0.026 (2) and 0.015 (2) Å, respectively]. The packing is stabilized by weak inter-molecular C-H⋯O and C-H⋯Br inter-actions.
منابع مشابه
(5S)-3-Chloro-5-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]-4-(4-methylpiperidin-1-yl)furan-2(5H)-one
The title compound, C(20)H(32)ClNO(3), was obtained via a tandem asymmetric Michael addition-elimination reaction of (5S)-3,4-dichloro-5-(l-menth-yloxy)furan-2(5H)-one and 4-methyl-piperidine in the presence of potassium fluoride. The furan-one ring is approximately planar [maximum atomic deviation = 0.022 (2) Å] while the cyclo-hexane ring adopts a chair conformation. Weak inter-molecular C-H⋯...
متن کاملMethyl 2-[(4-chloro-2-methoxy-5-oxo-2,5-dihydrofuran-3-yl)amino]acetate
The title compound, C(8)H(10)ClNO(5), was obtained via a tandem Michael addition-elimination reaction of 3,4-dichloro-5-meth-oxy-furan-2(5H)-one and glycine methyl ester in the presence of triethyl-amine. The mol-ecular structure contains an approximately planar [maximum atomic deviation = 0.010 (2) Å] five-membered furan-one ring. The crystal packing is stabilized by inter-molecular N-H⋯O and ...
متن کامل(S)-3-Chloro-4-(4-ethylpiperazin-1-yl)-5-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]furan-2(5H)-one
The title compound, C(20)H(33)ClN(2)O(3), was obtained via a tandem asymmetric Michael addition-elimination reaction of 3,4-dichloro-5-(S)-(l-menth-yloxy)furan-2(5H)-one and 1-ethyl-piperazine in the presence of potassium fluoride. The mol-ecular structure contains an approximately planar five-membered furan-one ring [maximum atomic deviation = 0.024 (2) Å] and two six-membered rings adopting c...
متن کامل(S)-3-Bromo-4-diallylamino-5-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]furan-2(5H)-one
The title compound, C(20)H(30)BrNO(3), was obtained via a tandem asymmetric Michael addition-elimination reaction of 3,4-dibromo-5-(S)-(l-menth-yloxy)-2(5H)-furan-one and diallyl-amine in the presence of potassium fluoride. In the mol-ecule, the five-membered furan-one ring is approximately planar [maximum atomic deviation = 0.030 (3) Å], and the six-membered cyclo-hexane ring adopts a chair co...
متن کامل2-(Furan-2-yl)-5-(2-nitrobenzyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
The title compound, C(20)H(16)N(2)O(4)S, was prepared by introduction of a 2-nitro-benzyl group to 2-(furan-2-yl)-2,3-dihydro-1,5-benzothia-zepin-4(5H)-one via an alkaline-catalysed reaction. The thia-zepine ring adopts a twist-boat conformation. The furan ring is oriented at dihedral angles of 56.75 (14) and 10.82 (14)° with respect to the two benzene rings, while the two benzene rings make a ...
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عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2011